Anti-anaemic potential of the hydro-ethanolic extract of Waltheria indica (L) in albino rats with parasitaemia – induced anaemia

Anaemia has been reported to be the key feature of trypanosomiasis and is used as primary indicator when treat infection. Therefore, this study was designed evaluate anti-anaemic potential hydro-ethanolic extract Waltheria indica in albino rats with parasitaemia – induced anaemia. Three groups 6 each were challenged Trypanosoma brucei induce anaemia treated 300mg/kg bw orally for 5 days, 3.5mg/kg Berenil® once intraperitoneally distilled water. All developed anaemia, manifested by significantly reduced values Packed Cell Volume (PCV), Haemoglobin (Hb)concentration Red Blood Cells (RBC) count within days infection compared pre-infection values. Treatment Berenil at led remarkable improvement PCV, Hb RBC, however, restoration (P < 0.05) higher animals ethanol plant. Results also indicated absence effect both treatment on levels erythrocyte indices (Mean Volume, Mean Concentration) infected rats. plant could use management African sleeping sickness other ailments related